Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
Blog Article
one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment of multiple myeloma. Its synthesis or study is essential for guaranteeing the purity and safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the output approach and making 5 sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the treatment method of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, 2-difluoro-D-erythro-pentofuranose-3 breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have different apps, which include antiviral properties.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to control style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).